Certified Hazardous Materials Manager (CHMM) Practice Exam 2025 - Free CHMM Practice Questions and Study Guide

The hematopoietic system is primarily responsible for the production and regulation of blood cells, and its exposure to toxins can lead to significant health issues. Lead is a well-known toxin that can interfere with red blood cell production and overall hematopoiesis, potentially causing anemia and other blood disorders. Nitrites, on the other hand, affect the blood by converting hemoglobin into methemoglobin, which reduces its ability to carry oxygen. However, the specific pairing of lead with nitrites in this context does not accurately reflect a recognized toxicological interaction motivating concern for the hematopoietic system, making it an incompatible couple.

In contrast, the other pairings presented contain elements that correspond correctly to their respective organ systems. PCBs (polychlorinated biphenyls) are persistent environmental pollutants with documented endocrine-disrupting effects, while carbon tetrachloride is known for its hepatotoxic effects alongside alcohol. Similarly, ammonia and chlorine are both hazardous substances that can affect the lymphatic system, albeit in a context typically more related to their impact on general health rather than a targeted lymphatic toxicity.

Thus, the alignment of toxins with their respective systems is crucial for understanding the pathways through which exposure can lead to disease, and the hematopo